San Francisco, California
Special Luncheon Hosted by Avant Diagnostics immediately following Keynote Address in Precision Medicine Track
Presentation by Dr. Emanuel Petricoin, “Beyond Genomics−Protein Drug Target Activation Mapping to Change the Paradigm in Precision Medicine Based Cancer Therapy”
The field of precision oncology now is extending beyond genomics to proteomic activation analysis since it is the protein activation machinery that contains nearly all of the drug targets. The reverse phase protein array platform can measure the activation state (phosphorylation) of the drug targets for nearly every targeted agent in the clinic, and produce a population-based portrait of functional activity or a patient-specific circuit diagram that can be used for treatment decision making.